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Microbial Pathogenesis

IHV was founded, in part, on an exceptional history of HIV research, a strength that continues to this day. Over the last nearly two decades, pathogenesis research in the Basic Science Division has expanded to encompass a variety of microbes, including Gram-positive and Gram-negative bacteria, Mycoplasma, Histoplasma, HTLV-1, respiratory viruses, hepatitis viruses and hemorrhagic fever viruses. Clinical samples and animal models, as well as genomic, proteomic, and metabolomic profiling are used to characterize diseased and healthy states.